Annals of Surgical Oncology - Society of Surgical Oncology

HIGHLIGHTED ARTICLES FROM ANNALS OF SURGICAL ONCOLOGY

Weekly Update

Adjuvant Chemoradiation in Resected Biliary Adenocarcinoma: Evaluation of SWOG S0809 with a Large National Database

Citation: Dominguez, D.A., Wong, P., Chen, YJ. et al. Adjuvant Chemoradiation in Resected Biliary Adenocarcinoma: Evaluation of SWOG S0809 with a Large National Database. Ann Surg Oncol (2024). https://doi.org/10.1245/s10434-024-15117-y

Synopsis: SWOG S0809 findings supported using the National Cancer Database, showing association of adjuvant chemoradiation in resected biliary cancer with improved overall survival compared to chemotherapy alone.

Expanding the Use of HIPEC in Ovarian Cancer at Time of Interval Debulking Surgery to FIGO Stage IV and After 6 Cycles of Neoadjuvant Chemotherapy: A Prospective Analysis on Perioperative and Oncologic Outcomes

April 18, 2024

Citation: Ghirardi, V., Trozzi, R., Scanu, F.R. et al. Expanding the Use of HIPEC in Ovarian Cancer at Time of Interval Debulking Surgery to FIGO Stage IV and After 6 Cycles of Neoadjuvant Chemotherapy: A Prospective Analysis on Perioperative and Oncologic Outcomes. Ann Surg Oncol 31, 3350–3360 (2024). https://doi.org/10.1245/s10434-024-15042-0

Synopsis: The outcomes of FIGO stage IV ovarian cancer patients and/or patients receiving up to VI cycles of NACT submitted to HIPEC at IDS have not been addressed in available randomized trials. In the authors’ experience, no difference in neither perioperative complications nor PFS outcomes was detected in both FIGO stage IV and/or patients receiving > IV cycles of NACT with respect to FIGO stage III and patients receiving up to IV cycles of NACT. The authors provide a background to consider offering HIPEC with cisplatin 100mg/m3 to selected FIGO stage IV patients and/or patients receiving up to VI cycles of NACT.

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