Surgical Oncology News

This section features a sampling of news related to surgical oncology from the popular press, from press releases received, or SSO news directly pertinent to SSO members.

Surgery may be avoided in early rectal cancer

Author: Neil Osterweil, Oncology Report Digital Network
Date:
Mar 26, 2013

Approximately 10%-25% of patients with locally advanced rectal cancer will have clinical complete responses (cCR) to neoadjuvant chemotherapy and radiation, said Dr. Philip B. Paty, an attending surgeon in the colorectal surgery service at Memorial Sloan-Kettering Cancer Center in New York City.

"The vast majority of these patients will avoid rectal resection, at least within the first 5 years," Dr. Paty added. "Although local failure occurs in 10%-25% of patients, most of the failures occur within the first 18 months, and most of these cases can be salvaged with R0 resections. Patients treated with nonoperative management appear to have rates of distant recurrence and survival similar to those of patients with pathologic complete responses (pCR) treated with total mesorectal resection," he said.

If surgery is required, local excision may be sufficient for some patients with stage T1 lesions and a select few with T2 lesions, said Dr. Heidi Nelson, professor of surgery in the department of colon and rectal surgery at the Mayo Clinic in Rochester, Minn.

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