Surgical Oncology News

This section features a sampling of news related to surgical oncology from the popular press, from press releases received, or SSO news directly pertinent to SSO members.

Predicting the Return of Bladder Cancer

Author: dailyRx News
May 09, 2013

Researchers found that patients with changes in various molecules were more likely to see their cancers recur.

Yair Lotan, MD, professor of urology at University of Texas Southwestern and the study’s primary investigator, and colleagues followed 216 bladder cancer patients to see if their cancers returned.

The patients had muscle-invasive bladder cancer, meaning the cancer had reached the muscles around the bladder.

Standard of care for invasive bladder cancer involves removing all or part of bladder. Chemotherapy may be given before surgery, but is rarely given after surgery, according to the authors.

The researchers tested tissues removed from the patients for five different molecular markers.

After controlling for variables relating to tumor characteristics and treatment variables including previous chemotherapy, the researchers found that the number of altered molecules was able to predict cancer return and mortality.

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