Breast Cancer Risk Models

BRCAPRO is a statistical model, with associated software, for assessing the probability that an individual carries a germline deleterious mutation of the BRCA1 and BRCA2 genes, based on family history of breast and ovarian cancer, based on his or her family's history of breast and ovarian cancer, including male breast cancer and bilateral synchronous and asynchronous diagnoses.  Breast Cancer Outcome Calculator web calculators provide medical professionals with tools for more accurately estimating the chance of survival for individual patients with breast cancer, melanoma, and renal cells carcinoma, and the impact that various treatment choices will have on that chance of survival.

Memorial Sloan-Kettering Cancer Center
Researchers at Memorial Sloan-Kettering Cancer Center have pioneered the use of computerized devices to help patients and their physicians decide among the major treatment choices for several cancers. Rather than relying on general risk groups of patient populations who share similar characteristics, our Breast Cancer Prediction Tools provide specific information.

National Cancer Institute Risk Prediction Resources 
This site aims to provide resources to clinicians and researchers who are developing new and improving existing models for cancer risk, validating these models and evaluating their utility in research and clinic settings. 

Breast Cancer Risk Assessment Tool
Based on a statistical model known as the 'Gail model,' which is named after Dr. Mitchell Gail, Senior Investigator in the Biostatistics Branch of NCI's Division of Cancer Epidemiology and Genetics.

Breast Cancer Risk Assessment: A Guide for Clinicians Using the NCCN Breast
Cancer Risk Reduction Guidelines

Sofia D. Merajver, MD, PhD, and Kara Milliron, MS, CGC, Ann Arbor, Michigan. © Journal of the National Comprehensive Cancer Network | Volume 1 Number 2 | April 2003