Recurrence Patterns and Survival Outcomes in Clinical Stage IIB/IIC Melanoma: Can We Stratify Patients for Consideration of Neoadjuvant Immunotherapy?

September 19, 2025.
Citation: Farooq, M.S., Mattfeld, V., Beniwal, P.C. et al. Recurrence Patterns and Survival Outcomes in Clinical Stage IIB/IIC Melanoma: Can We Stratify Patients for Consideration of Neoadjuvant Immunotherapy?. Ann Surg Oncol (2025). https://doi.org/10.1245/s10434-025-18263-z
Synopsis: In this single-institution retrospective cohort study of patients with clinical stage IIB/IIC melanoma, the authors found a 2-year recurrence-free survival of 69%, as well as a significant association of pre-surgical lymphovascular invasion with recurrence.