HIGHLIGHTED ARTICLES FROM ANNALS OF SURGICAL ONCOLOGY

Weekly Update

Konstantinos I. Votanopoulos, Steven Forsythe, Hemamylammal Sivakumar…Aleksander Skardal

Citation:  Votanopoulos, K.I., Forsythe, S., Sivakumar, H. et al. Model of Patient-Specific Immune-Enhanced Organoids for Immunotherapy Screening: Feasibility Study. Ann Surg Oncol 27, 1956–1967 (2020).
https://link.springer.com/article/10.1245%2Fs10434-019-08143-8 

Synopsis: The authors describe a patient-specific organoid platform, where melanoma and lymph node from the same patient are cocultured and used to predict tumor response to immunotherapy and generate adaptive immunity, by presenting tumor neoantigens on patient’s own nodal antigen-presenting cells (APCs). 

Korrel, J. van Hilst, A. Alseidi…M. G. Besselink

Citation: Korrel, M., Lof, S., van Hilst, J. et al. Predictors for Survival in an International Cohort of Patients Undergoing Distal Pancreatectomy for Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol (2020).
 https://link.springer.com/article/10.1245/s10434-020-08658-5 

Synopsis: It is unclear which predictors related to surgical technique are associated with improved overall survival after distal pancreatectomy for pancreatic ductal adenocarcinoma. In this international cohort including 1200 patients, predictors for improved overall survival included Gerota’s fascia resection, R0-resection, and decreased lymph node ratio.

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ASO – The Leading Resource in Surgical Oncology

Annals of Surgical OncologyAnnals of Surgical Oncology (ASO) hails 2019 as a year of growth and influence with a 13% increase in editorials, the addition of a two new editorial sections and the introduction of “ASO Author Reflections.” ASO also had more than 1 million article downloads, a demonstration of the quality and relevance of the research published. Read more about ASO.

ASO is the journal of choice of surgical oncologists and cancer multidisciplinary teams worldwide regarding surgical oncology research and education, and benefits surgeons, oncologists, hematologists, radiologists, general practitioners, pathologists, researchers, academicians, and other clinical professionals interested in all aspects of the surgical treatment of cancer. ASO strives to improve the practice environment in which high-quality surgical oncology care is delivered, to enhance the quality of life and survival of the surgical patient with cancer.

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