HIGHLIGHTED ARTICLES FROM ANNALS OF SURGICAL ONCOLOGY
Konstantinos I. Votanopoulos, Steven Forsythe, Hemamylammal Sivakumar…Aleksander Skardal
Citation: Votanopoulos, K.I., Forsythe, S., Sivakumar, H. et al. Model of Patient-Specific Immune-Enhanced Organoids for Immunotherapy Screening: Feasibility Study. Ann Surg Oncol 27, 1956–1967 (2020).
Synopsis: The authors describe a patient-speciﬁc organoid platform, where melanoma and lymph node from the same patient are cocultured and used to predict tumor response to immunotherapy and generate adaptive immunity, by presenting tumor neoantigens on patient’s own nodal antigen-presenting cells (APCs).
Korrel, J. van Hilst, A. Alseidi…M. G. Besselink
Citation: Korrel, M., Lof, S., van Hilst, J. et al. Predictors for Survival in an International Cohort of Patients Undergoing Distal Pancreatectomy for Pancreatic Ductal Adenocarcinoma. Ann Surg Oncol (2020).
Synopsis: It is unclear which predictors related to surgical technique are associated with improved overall survival after distal pancreatectomy for pancreatic ductal adenocarcinoma. In this international cohort including 1200 patients, predictors for improved overall survival included Gerota’s fascia resection, R0-resection, and decreased lymph node ratio.
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