HIGHLIGHTED ARTICLES FROM ANNALS OF SURGICAL ONCOLOGY
Weekly Update
Plasma Exosome Gene Signature Differentiates Colon Cancer from Healthy Controls

March 9, 2023
Citation:
Vallejos, P.A., Gonda, A., Yu, J. et al. Plasma Exosome Gene Signature Differentiates Colon Cancer from Healthy Controls. Ann Surg Oncol (2023). https://doi.org/10.1245/s10434-023-13219-7
Synopsis: Current liquid biopsy options lack sensitivity in peritoneal carcinomatosis (PC). In this initial feasibility analysis, we have identified a plasma exosome-based gene signature of 445 genes from colon cancer patients, including those with PC, that is distinct from healthy controls.
Preoperative Partial Breast Irradiation in Patients with Low-Risk Breast Cancer: A Systematic Review of Literature
March 9, 2023
Citation:
Civil, Y.A., Jonker, L.W., Groot Koerkamp, M.P.M. et al. Preoperative Partial Breast Irradiation in Patients with Low-Risk Breast Cancer: A Systematic Review of Literature. Ann Surg Oncol (2023). https://doi.org/10.1245/s10434-023-13233-9
Synopsis: This systematic review shows that pre-operative partial breast irradiation is a feasible treatment option in patients with low-risk breast cancer. Pathologic complete response was reported in almost half of the patients with acceptable toxicity, good oncological and cosmetic outcomes.

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