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Annals of Surgical Oncology

HIGHLIGHTED ARTICLES FROM ANNALS OF SURGICAL ONCOLOGY

Weekly Update

Local-Regional Recurrence After Neoadjuvant Endocrine Therapy: Data from ACOSOG Z1031 (Alliance), a Randomized Phase 2 Neoadjuvant Comparison Between Letrozole, Anastrozole, and Exemestane for Postmenopausal Women with Estrogen Receptor-Positive Clinical Stage 2 or 3 Breast Cancer

Local Regional Recurrence After Neoadjuvant Endocrine Therapy

February 2. 2023

Hunt, K.K., Suman, V.J., Wingate, H.F. et al. Local-Regional Recurrence After Neoadjuvant Endocrine Therapy: Data from ACOSOG Z1031 (Alliance), a Randomized Phase 2 Neoadjuvant Comparison Between Letrozole, Anastrozole, and Exemestane for Postmenopausal Women with Estrogen Receptor-Positive Clinical Stage 2 or 3 Breast Cancer. Ann Surg Oncol (2023). https://doi.org/10.1245/s10434-022-12972-5

Synopsis: ACOSOG Z1031 (Alliance) was designed to determine which aromatase inhibitor is most effective for postmenopausal women with estrogen receptor–positive stage 2 to 3 breast cancer in the neoadjuvant setting. The local-regional recurrence rate of 509 women is reported here.

Improved Adherence to ATA Medullary Thyroid Cancer Treatment Guidelines

February 2, 2023

McMullin, J.L., Sharma, J., Gillespie, T. et al. Improved Adherence to ATA Medullary Thyroid Cancer Treatment Guidelines. Ann Surg Oncol (2022). https://doi.org/10.1245/s10434-022-12734-3

Synopsis:  The 2009 ATA guidelines for medullary thyroid cancer were created to unify national practice patterns. Treatment was discordant from guidelines in 26% of cases after 2009 compared to 33% prior. Improved adherence to guidelines correlates with improved overall survival.

Improved Adherence to ATA Medullary Thyroid Cancer Treatment Guidelines

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The series is hosted by ASO Deputy Editor Dr. Frederick L. (Rick) Greene, who will expand upon ideas from articles published in the Annals. Once a month, Dr. Greene will interview authors and leading experts in surgical oncology.

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